Determining of Apoptosis at in vitro Conditioned DRG Neurons with TUNEL Method
نویسندگان
چکیده
منابع مشابه
Role of a voltage-sensitive calcium channel blocker on inhibition of apoptosis in sensory neurons of cultured dorsal root ganglia in adult rat
Introduction: Under pathological conditions, abnormal increase in intracellular calcium concentrations is believed to induce cell death. In the present study, a voltage-sensitive calcium channel blocker (loperamide hydrochloride) was used to investigate its role in inhibition of apoptosis in sensory neurons of cultured spinal dorsal root ganglia (DRG). Methods: L5 DRG from adult rats were di...
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Programmed cell death is a combined intracellular process. For the activation of apoptosis as proapoptotic genes and antiapoptotic ones are needed as well. There are several methods of apoptosis assessment but in laryngeal cancer prognostic value of apoptotic index is still unclear. 44 patients with laryngeal cancer who received surgical treatment in ENT Department of Medical University of Lodz...
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The in situ detection of cells undergoing apoptosis is increasingly important in the analysis of injury and degeneration in the central nervous system. Limited information is presently available on the quantification of apoptosis in paraffin-embedded brain tissue sections, a technique which would be most useful in the evaluation of archival tissue for diagnostic and experimental purposes. In th...
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Background: Auxiliary subunits regulate the voltage-gated sodium channels of DRG neurons. Results: subunits are differentially expressed in subpopulations of DRG neurons and regulate Nav1.7 channels in an isoform-specific manor. Conclusions: Differential subunit expression and isoform-specific regulation has important implications for the sodium currents of DRG neurons. Significance: su...
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The aim of the present study was to evaluate the distribution of apoptotic neurons in the nuclei of the brainstem. Apoptosis was studied by the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assay, in human brainstems taken at autopsy from 15 adults (age range: 25-58 years). The nuclei examined included the hypoglossal nucleus (XII), dorsal motor nucleus of the va...
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ژورنال
عنوان ژورنال: Bitlis Eren University Journal of Science and Technology
سال: 2017
ISSN: 2146-7706
DOI: 10.17678/beuscitech.331471